منابع مشابه
Mass spectrometry-based metabolomics.
This review presents an overview of the dynamically developing field of mass spectrometry-based metabolomics. Metabolomics aims at the comprehensive and quantitative analysis of wide arrays of metabolites in biological samples. These numerous analytes have very diverse physico-chemical properties and occur at different abundance levels. Consequently, comprehensive metabolomics investigations ar...
متن کاملMass spectrometry-based metabolomics
untargeted. Targeted metabolomics focuses on a subset of metabolites involved in one or more pathways; the chemical identities of metabolites to be measured are known, authentic standards are available in these studies. The goal of untargeted metabolomics is to observe global metabolite profiling differences between sample types, experiments are designed to maximise the coverage of metabolites....
متن کاملInformatics for tandem mass spectrometry-based metabolomics
Metabolomics is a rapidly expanding field with applications in areas such as medicine, agriculture, or food safety. Tandem mass spectrometry (MS) is one of the main technologies that drives the field forward. Optionally coupled to a chromatographic element, MS can capture detailed snapshots of an organism’s metabolome. The resulting data sets are complex and difficult to analyse due to the mult...
متن کاملMET-IDEA: data extraction tool for mass spectrometry-based metabolomics.
A current and significant limitation to metabolomics is the large-scale, high-throughput conversion of raw chromatographically coupled mass spectrometry datasets into organized data matrices necessary for further statistical processing and data visualization. This article describes a new data extraction tool, MET-IDEA (Metabolomics Ion-based Data Extraction Algorithm) which surmounts this void....
متن کاملEvaluating plant immunity using mass spectrometry-based metabolomics workflows
Metabolic processes in plants are key components of physiological and biochemical disease resistance. Metabolomics, the analysis of a broad range of small molecule compounds in a biological system, has been used to provide a systems-wide overview of plant metabolism associated with defense responses. Plant immunity has been examined using multiple metabolomics workflows that vary in methods of ...
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ژورنال
عنوان ژورنال: Mass Spectrometry Reviews
سال: 2006
ISSN: 0277-7037
DOI: 10.1002/mas.20108